Stats
2022-2023
| 52 | 128 | 61 | 81 | 4 | 34 | 10 | 8 |
| Patrick van Aanholt | 21 | 2 | 3 | 2 | 8 | 2 | 0 |
| Johan Bakayoko | 33 | 7 | 5 | 9 | 19 | 4 | 0 |
| Walter Benitez | 42 | 0 | 0 | 0 | 0 | 3 | 0 |
| Emmanuel van de Blaak | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
| Olivier Boscagli | 8 | 1 | 1 | 6 | 0 | 0 | 0 |
| Jarrad Branthwaite | 35 | 4 | 2 | 8 | 4 | 2 | 0 |
| Joël Drommel | 10 | 0 | 0 | 0 | 0 | 0 | 0 |
| Cody Gakpo | 24 | 13 | 17 | 0 | 9 | 1 | 0 |
| Anwar El Ghazi | 31 | 9 | 2 | 17 | 12 | 5 | 1 |
| Marco van Ginkel | 4 | 0 | 0 | 4 | 0 | 1 | 0 |
| Erick Gutiérrez | 44 | 5 | 3 | 23 | 6 | 7 | 0 |
| Thorgan Hazard | 13 | 2 | 1 | 12 | 1 | 1 | 0 |
| Ki-Jana Hoever | 8 | 0 | 2 | 4 | 3 | 0 | 0 |
| Luuk de Jong | 39 | 18 | 9 | 3 | 22 | 5 | 0 |
| Richard Ledezma | 11 | 0 | 0 | 9 | 1 | 2 | 0 |
| Derrick Luckassen | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Noni Madueke | 9 | 2 | 0 | 5 | 1 | 2 | 0 |
| Mauro Junior | 11 | 0 | 0 | 8 | 1 | 0 | 2 |
| Philipp Max | 25 | 0 | 2 | 2 | 11 | 3 | 0 |
| Phillipp Mwene | 38 | 0 | 2 | 10 | 7 | 4 | 0 |
| Armando Obispo | 33 | 3 | 2 | 2 | 13 | 4 | 1 |
| Fredrik Oppegård | 6 | 0 | 0 | 4 | 0 | 0 | 0 |
| Kjell Peersman | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Andre Ramalho | 45 | 0 | 1 | 12 | 8 | 6 | 0 |
| Ismael Saibari | 28 | 0 | 2 | 16 | 9 | 1 | 0 |
| Ibrahim Sangaré | 45 | 8 | 2 | 3 | 7 | 7 | 0 |
| Savió | 8 | 0 | 2 | 8 | 0 | 0 | 0 |
| Fábio Silva | 19 | 5 | 1 | 13 | 2 | 3 | 0 |
| Xavi Simons | 48 | 22 | 11 | 3 | 24 | 7 | 0 |
| Jordan Teze | 43 | 0 | 5 | 8 | 8 | 4 | 0 |
| Guus Til | 46 | 13 | 5 | 15 | 22 | 5 | 0 |
| Joey Veerman | 50 | 9 | 14 | 3 | 20 | 2 | 0 |
| Yorbe Vertessen | 12 | 2 | 0 | 9 | 3 | 0 | 0 |
| Carlos Vinicius | 2 | 0 | 0 | 2 | 0 | 0 | 0 |
| Boy Waterman | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Trainers
| Ruud van Nistelrooij | 51 |
| Fred Rutten | 1 |
Uitslagen
| 30-07-22 | JCS | Ajax | 3-5 |
| 02-08-22 | CL | AS Monaco | 1-1 |
| 06-08-22 | E | FC Emmen | 4-1 |
| 09-08-22 | CL | AS Monaco | 3-2 |
| 13-08-22 | E | Go Ahead Eagles | 2-5 |
| 16-08-22 | CL | Rangers FC | 2-2 |
| 24-08-22 | CL | Rangers FC | 0-1 |
| 28-08-22 | E | Excelsior | 1-6 |
| 31-08-22 | E | FC Volendam | 7-1 |
| 03-09-22 | E | FC Twente | 2-1 |
| 08-09-22 | EL | FK Bodø/Glimt | 1-1 |
| 11-09-22 | E | RKC Waalwijk | 1-0 |
| 18-09-22 | E | Feyenoord | 4-3 |
| 01-10-22 | E | SC Cambuur | 3-0 |
| 06-10-22 | EL | FC Zürich | 1-5 |
| 09-10-22 | E | sc Heerenveen | 0-1 |
| 13-10-22 | EL | FC Zürich | 5-0 |
| 16-10-22 | E | FC Utrecht | 6-1 |
| 20-10-22 | EL | Arsenal FC | 1-0 |
| 23-10-22 | E | FC Groningen | 4-2 |
| 27-10-22 | EL | Arsenal FC | 2-0 |
| 30-10-22 | E | NEC | 3-0 |
| 03-11-22 | EL | FK Bodø/Glimt | 1-2 |
| 06-11-22 | E | Ajax | 1-2 |
| 12-11-22 | E | AZ | 0-1 |
| 07-01-23 | E | Sparta Rotterdam | 0-0 |
| 10-01-23 | B | Sparta Rotterdam | 1-2 |
| 15-01-23 | E | Fortuna Sittard | 2-2 |
| 21-01-23 | E | Vitesse | 1-0 |
| 24-01-23 | E | FC Emmen | 1-0 |
| 28-01-23 | E | Go Ahead Eagles | 2-0 |
| 05-02-23 | E | Feyenoord | 2-2 |
| 08-02-23 | B | FC Emmen | 3-1 |
| 11-02-23 | E | FC Groningen | 6-0 |
| 16-02-23 | EL | Sevilla FC | 3-0 |
| 19-02-23 | E | FC Utrecht | 2-2 |
| 23-02-23 | EL | Sevilla FC | 2-0 |
| 26-02-23 | E | FC Twente | 3-1 |
| 02-03-23 | B | ADO Den Haag | 3-1 |
| 05-03-23 | E | RKC Waalwijk | 0-1 |
| 12-03-23 | E | SC Cambuur | 5-2 |
| 19-03-23 | E | Vitesse | 1-1 |
| 01-04-23 | E | NEC | 2-4 |
| 04-04-23 | B | Spakenburg | 1-2 |
| 08-04-23 | E | Excelsior | 4-0 |
| 16-04-23 | E | FC Volendam | 2-3 |
| 23-04-23 | E | Ajax | 3-0 |
| 30-04-23 | B | Ajax | 1-1 |
| 06-05-23 | E | Sparta Rotterdam | 0-1 |
| 14-05-23 | E | Fortuna Sittard | 2-1 |
| 21-05-23 | E | sc Heerenveen | 3-3 |
| 28-05-23 | E | AZ | 1-2 |
Eredivisie
 |
Feyenoord CL | 34 | 25 | 7 | 2 | 82 | 81-30 |
 |
PSV vCL | 34 | 23 | 6 | 5 | 75 | 89-40 |
 |
Ajax vEL | 34 | 20 | 9 | 5 | 69 | 86-38 |
 |
AZ vECL | 34 | 20 | 7 | 7 | 67 | 68-35 |
 |
FC Twente PO vECL | 34 | 18 | 10 | 6 | 61 | 66-27 |
 |
Sparta Rotterdam PO | 34 | 17 | 8 | 9 | 59 | 60-37 |
 |
FC Utrecht PO | 34 | 15 | 9 | 10 | 54 | 55-50 |
 |
sc Heerenveen PO | 34 | 12 | 10 | 12 | 46 | 44-50 |
 |
RKC Waalwijk | 34 | 11 | 8 | 15 | 41 | 50-64 |
 |
Vitesse | 34 | 10 | 10 | 14 | 40 | 45-50 |
 |
Go Ahead Eagles | 34 | 10 | 10 | 14 | 40 | 46-56 |
 |
NEC | 34 | 8 | 15 | 11 | 39 | 42-45 |
 |
Fortuna Sittard | 34 | 10 | 6 | 18 | 36 | 39-62 |
 |
FC Volendam | 34 | 10 | 6 | 18 | 36 | 42-71 |
 |
Excelsior | 34 | 9 | 5 | 20 | 32 | 32-71 |
 |
FC Emmen PO D | 34 | 6 | 10 | 17 | 28 | 33-65 |
 |
SC Cambuur D | 34 | 5 | 4 | 25 | 19 | 26-69 |
 |
FC Groningen D | 34 | 4 | 6 | 24 | 18 | 31-70 |
CL = Champions League | vCL = voorronde Champions League | vEL = voorronde Europa League | vECL = voorronde Europa Conference League | PO = playoffs | D = degradatie
Heracles Almelo kampioen Keuken Kampioen Divisie | Promotie voor PEC Zwolle en Almere City FC
Europa League
 |
Arsenal FC | 6 | 5 | 0 | 1 | 15 | 8-3 |
|
|
PSV | 6 | 4 | 1 | 1 | 13 | 15-4 |
 |
FK Bodø/Glimt | 6 | 1 | 1 | 4 | 4 | 5-10 |
 |
FC Zürich | 6 | 1 | 0 | 5 | 3 | 5-16 |
Topscorers Eredivisie
| Xavi Simons | PSV | 19 |
| Anastasios Douvikas | FC Utrecht | 19 |
| Sydney van Hooijdonk | sc Heerenveen | 16 |
| Santiago Giménez | Feyenoord | 15 |
| Luuk de Jong | PSV | 14 |
| Brian Brobbey | Ajax | 13 |
| Vaclav Cerny | FC Twente | 13 |
| Michiel Kramer | RKC Waalwijk | 12 |
| Vangelis Pavlidis | AZ | 12 |
| Ricardo Pepi | FC Groningen | 12 |
| Steven Bergwijn | Ajax | 12 |
| Tobias Lauritsen | Sparta Rotterdam | 12 |
| Vito van Crooij | Sparta Rotterdam | 12 |
| Dusan Tadic | Ajax | 11 |
| Mohammed Kudus | Ajax | 11 |
| Ole Romeny | FC Emmen | 11 |
| Danilo | Feyenoord | 10 |
| Landry Dimata | NEC | 10 |
Topscorers PSV Eredivisie
| Xavi Simons | 19 |
| Luuk de Jong | 14 |
| Cody Gakpo | 9 |
| Guus Til | 9 |
| Anwar El Ghazi | 8 |
| Johan Bakayoko | 5 |
| Ibrahim Sangaré | 5 |
| Joey Veerman | 4 |
| Fábio Silva | 4 |
| Erick Gutiérrez | 2 |
| Jarrad Branthwaite | 2 |
| Armando Obispo | 2 |
| Patrick van Aanholt | 1 |
| Olivier Boscagli | 1 |
| Thorgan Hazard | 1 |
| Noni Madueke | 1 |